|
Age in Years
|
|
18 to 30
|
13 (5.1%)
|
4 (3.9%)
|
17 (4.8%)
|
|
31 to 40
|
37 (14.6%)
|
9 (8.7%)
|
46 (12.9%)
|
|
41 to 50
|
74 (29.2%)
|
18 (17.5%)
|
92 (25.8%)
|
|
51 to 60
|
58 (22.9%)
|
36 (35%)
|
94 (26.4%)
|
|
61 to 70
|
45 (17.8%)
|
26 (25.2%)
|
71 (19.9%)
|
|
> 70
|
26 (10.3%)
|
10 (9.7%)
|
36 (10.1%)
|
|
Body Weight (kg), mean (SD)
|
72.7 (14.9)
|
73.7 (15.3)
|
73.0 (15.0)
|
|
Sex (n,%)
|
|
Female
|
162 (64%)
|
69 (67%)
|
231 (64.9%)
|
|
Male
|
91 (36%)
|
34 (33%)
|
125 (35.1%)
|
|
Previous Surgery (n,%)
|
|
No
|
248 (98%)
|
100 (97.1%)
|
348 (97.8%)
|
|
Yes
|
5 (2%)
|
3 (2.9%)
|
8 (2.2%)
|
|
Prior Treatment with BoNT-A (n,%)
|
|
No
|
49 (19.4%)
|
7 (6.8%)
|
56 (15.7%)
|
|
Yes
|
204 (80.6%)
|
96 (93.2%)
|
300 (84.3%)
|
|
Tremor (n,%)
|
|
Absent
|
142 (56.1%)
|
41 (39.8%)
|
183 (51.4%)
|
|
Present
|
111 (43.9%)
|
62 (60.2%)
|
173 (48.6%)
|
|
Predominant Component (n,%)
|
|
Not Rotation
|
49 (19.4%)
|
38 (36.9%)
|
87 (24.4%)
|
|
Rotation
|
204 (80.6%)
|
65 (63.1%)
|
269 (75.6%)
|
|
EMG at Baseline (n,%)
|
|
No
|
151 (59.7%)
|
40 (38.8%)
|
191 (53.7%)
|
|
Yes
|
102 (40.3%)
|
63 (61.2%)
|
165 (46.3%)
|
|
TWSTRS Scores at Baseline
|
|
Total Score, mean (SD)
|
37.8 (9.4)
|
33.9 (11.1)
|
37.1 (10.2)
|
|
Severity Subscale Score, mean (SD)
|
20.1 (3.5)
|
18.9 (3.4)
|
19.8 (3.5)
|
|
Disability Subscale Score, mean (SD)
|
11.1 (5.3)
|
9.2 (6.0)
|
10.7 (5.6)
|
|
Pain Subscale Score, mean (SD)
|
6.6 (4.7)
|
5.8 (4.9)
|
6.6 (4.8)
|
|
EQ-5D Utility Score at Baseline, mean (SD)
|
0.56 (0.03)
|
0.57 (0.03)
|
0.57 (0.03)
|
|
Total Injected Units of BoNT-A, mean (SD)
|
598.8 (231.9)
|
172.9 (66.5)
|
–
|
