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Table 3 Mean Change in Outcomes and at 3-year Visit

From: Characterization of vitamin D supplementation and clinical outcomes in a large cohort of early Parkinson’s disease

 

No D Supplement (N = 511)

MVI (N = 322)

D (N = 42)

D + MVI (N = 68)

P value

Mean (SD)

F test

Change in UPDRS total

5.5 (11.8)

6.2 (12.0)

4.9 (9.8)

9.2 (14.3)

0.12

Change in UPDRS mental

0.5 (1.5)

0.5 (1.5)

0.6 (2.0)

0.6 (1.8)

0.83

Change in UPDRS ADL

2.0 (4.4)

2.3 (4.5)

1.9 (3.6)

3.0 (4.7)

0.30

Change in PDQ 39 summary

4.6 (10.4)

4.3 (9.6)

4.0 (11.3)

4.8 (10.5)

0.96

Change in SDMT

0.002 (9.5)

−0.2 (9.4)

−1.6 (11.0)

−0.8 (13.3)

0.73

Change in Total daily LED

294.6 (367.1)

268.4 (339.8)

220.6 (244.5)

271.5 (346.4)

0.48

  1. Abbreviations: UPDRS Unified Parkinson’s Disease Rating Scale, ADL activities of daily living, PDQ Parkinson’s disease questionnaire, SDMT symbol digit modalities test, LED levodopa equivalent dose