Skip to main content

Table 2 Demographic, medical history and clinical characteristics at baseline

From: Spectrum of practice in the routine management of cervical dystonia with abobotulinumtoxinA: findings from three prospective open-label observational studies

Characteristic

AbobotulinumtoxinA treated subjects (N = 1202)

Sex (female); n (%)

797 (66.3)

Age; n (%)

 18–30

50 (4.2)

 31–40

118 (9.8)

 41–50

261 (21.7)

 51–60

306 (25.5)

 61–70

295 (24.5)

  > 70

172 (14.3)

Proportion subjects with CD family history; n (%)

85 (7.1)

Time since diagnosis (years); n (%)

  < 1

149 (12.4)

 1–5

415 (34.6)

  > 5

637 (53.0)

 Missing

1

Previous treatment with BoNT; n (%)

 Yes

994 (82.8)

 No

206 (17.2)

 Missing

2

Use of concomitant medication; n (%)

453 (37.7)

Proportion with simple CD; n (%)*

373 (31.1)

Proportion with complex CD; n (%)

821 (68.4)

Predominant head/neck deviation pattern; n (%)

 Torticollis

758 (64.1)

 Laterocollis

243 (20.5)

 Retrocollis

57 (4.8)

 Anterocollis

24 (2.0)

 Lateral shift

11 (0.9)

 Sagittal shift

10 (0.8)

 Missing/not derived

99

Secondary head/neck deviation pattern and associated components; n (%)

 Torticollis

283 (34.3)

 Laterocollis

468 (56.7)

 Retrocollis

200 (24.2)

 Anterocollis

151 (18.3)

 Lateral shift

170 (20.6)

 Sagittal shift

78 (9.5)

 No secondary pattern

68 (5.7)

 Missing/not derived

309

CD component; n (%)

 Shoulder elevation; n (%)

499 (71.6)

 Tremor; n (%)

393 (56.4)

 Jerk; n (%)

86 (12.3)

 No component

164

 Missing

341

Tsui tremor score category; n (%)

 0

445 (47.2)

 1

238 (25.3)

 2

155 (16.5)

 4

104 (11.0)

Missing

260

Tsui tremor severity category; n (%)

 None

445 (47.2)

 Mild

381 (40.4)

 Severe

116 (12.3)

 Missing

260

Tsui tremor duration category; n (%)

 None

445 (47.2)

 Occasional

250 (26.5)

 Continuous

247 (26.2)

 Missing

260

TWSTRS Total; mean ± SD**

33.95 ± 12.46

TWSTRS Severity; mean ± SD**

17.18 ± 5.13

TWSTRS Disability; mean ± SD**

9.95 ± 6.30

TWSTRS Pain; mean ± SD**

6.82 ± 4.94

  1. *6 subjects had no pattern. **Missing data for one subject
  2. BoNT botulinum neurotoxin, CD cervical dystonia, SD standard deviation, TWSTRS Toronto Western Spasmodic Torticollis Rating Scale