Case(N = 14) | Control(N = 14) | |||||||
---|---|---|---|---|---|---|---|---|
Factor | n | Baseline | Endpoint | P value | n | Baseline | Endpoint | P value |
ESS Total | 8 | 11.1 ± 4.9 | 8.4 ± 5.9 | 0.042 | 12 | 9.8 ± 6.2 | 9.0 ± 4.5 | 0.40 |
FSS Total | 8 | 27.3 ± 13.1 | 21.3 ± 11.0 | 0.21 | 12 | 30.5 ± 11.5 | 28.2 ± 11.2 | 0.35 |
ISI Total | 8 | 15.7 ± 3.0 | 7.8 ± 4.4 | 0.002 | 12 | 15.3 ± 3.0 | 12.2 ± 5.5 | 0.033 |
UPDRS1b Total | 8 | 9.8 ± 4.0 | 6.9 ± 3.1 | 0.004 | 12 | 9.7 ± 1.8 | 8.6 ± 2.4 | 0.037 |
UPDRS1b Modified | 8 | 5.4 ± 3.4 | 4.4 ± 2.1 | 0.35 | 12 | 5.4 ± 1.7 | 4.8 ± 1.6 | 0.77 |
UPDRS2 total | 8 | 12.6 ± 7.9 | 12.3 ± 6.3 | 0.93 | 12 | 10.9 ± 7.1 | 10.6 ± 8.4 | 0.99 |
PDQ Total | 7 | 14.4 ± 4.4 | 13.7 ± 3.7 | 0.53 | 11 | 15.6 ± 5.8 | 13.1 ± 3.8 | 0.73 |
PHQ9 Total | 8 | 7.8 ± 5.1 | 3.5 ± 4.5 | 0.005 | 12 | 7.5 ± 4.2 | 5.4 ± 3.3 | 0.17 |
pirs20 Total | 8 | 9.1 ± 2.4 | 5.0 ± 2.3 | <0.001 | 12 | 9.2 ± 2.1 | 7.4 ± 3.9 | 0.14 |
EQ5D Index | 8 | 0.75 ± 0.15 | 0.71 ± 0.17 | 0.24 | 12 | 0.79 ± 0.13 | 0.77 ± 0.17 | 0.55 |