| |
Case(N = 14)
|
Control(N = 14)
|
|---|
|
Factor
|
n
|
Baseline
|
Endpoint
|
P value
|
n
|
Baseline
|
Endpoint
|
P value
|
|---|
|
ESS Total
|
8
|
11.1 ± 4.9
|
8.4 ± 5.9
|
0.042
|
12
|
9.8 ± 6.2
|
9.0 ± 4.5
|
0.40
|
|
FSS Total
|
8
|
27.3 ± 13.1
|
21.3 ± 11.0
|
0.21
|
12
|
30.5 ± 11.5
|
28.2 ± 11.2
|
0.35
|
|
ISI Total
|
8
|
15.7 ± 3.0
|
7.8 ± 4.4
|
0.002
|
12
|
15.3 ± 3.0
|
12.2 ± 5.5
|
0.033
|
|
UPDRS1b Total
|
8
|
9.8 ± 4.0
|
6.9 ± 3.1
|
0.004
|
12
|
9.7 ± 1.8
|
8.6 ± 2.4
|
0.037
|
|
UPDRS1b Modified
|
8
|
5.4 ± 3.4
|
4.4 ± 2.1
|
0.35
|
12
|
5.4 ± 1.7
|
4.8 ± 1.6
|
0.77
|
|
UPDRS2 total
|
8
|
12.6 ± 7.9
|
12.3 ± 6.3
|
0.93
|
12
|
10.9 ± 7.1
|
10.6 ± 8.4
|
0.99
|
|
PDQ Total
|
7
|
14.4 ± 4.4
|
13.7 ± 3.7
|
0.53
|
11
|
15.6 ± 5.8
|
13.1 ± 3.8
|
0.73
|
|
PHQ9 Total
|
8
|
7.8 ± 5.1
|
3.5 ± 4.5
|
0.005
|
12
|
7.5 ± 4.2
|
5.4 ± 3.3
|
0.17
|
|
pirs20 Total
|
8
|
9.1 ± 2.4
|
5.0 ± 2.3
|
<0.001
|
12
|
9.2 ± 2.1
|
7.4 ± 3.9
|
0.14
|
|
EQ5D Index
|
8
|
0.75 ± 0.15
|
0.71 ± 0.17
|
0.24
|
12
|
0.79 ± 0.13
|
0.77 ± 0.17
|
0.55
|
- Values presented as Mean ± SD. p-values: paired t test
- Bold values are statistically significant p < 0.05
