| |
Case(N = 14)
|
Control(N = 14)
|
|---|
|
Factor
|
Baseline
|
Endpoint
|
P value
|
Baseline
|
Endpoint
|
P value
|
|---|
|
ESS Total
|
11.1 ± 4.9
|
9.5 ± 5.8
|
0.048
|
9.3 ± 6.2
|
8.1 ± 4.8
|
0.25
|
|
FSS Total
|
27.3 ± 13.1
|
25.4 ± 13.6
|
0.20
|
29.1 ± 12.2
|
29.2 ± 12.6
|
0.70
|
|
ISI Total
|
15.7 ± 3.0
|
11.2 ± 5.6
|
0.007
|
15.4 ± 2.9
|
12.2 ± 5.1
|
0.008
|
|
UPDRS1b Total
|
9.8 ± 4.0
|
8.1 ± 4.2
|
0.010
|
9.4 ± 2.1
|
8.4 ± 2.5
|
0.043
|
|
UPDRS1b Modified
|
5.4 ± 3.4
|
5.0 ± 3.2
|
0.34
|
5.1 ± 2.0
|
4.9 ± 1.7
|
0.58
|
|
UPDRS2 total
|
12.6 ± 7.9
|
12.5 ± 7.0
|
0.93
|
10.4 ± 7.1
|
10.2 ± 8.0
|
0.77
|
|
PDQ Total
|
14.4 ± 4.4
|
14.2 ± 4.3
|
0.52
|
15.2 ± 5.8
|
14.6 ± 5.6
|
0.32
|
|
PHQ9 Total
|
7.8 ± 5.1
|
5.8 ± 5.5
|
0.011
|
7.2 ± 4.2
|
5.9 ± 4.1
|
0.14
|
|
pirs20 Total
|
9.1 ± 2.4
|
7.2 ± 3.5
|
0.004
|
9.1 ± 2.1
|
7.5 ± 3.9
|
0.070
|
|
EQ5D Index
|
0.75 ± 0.15
|
0.72 ± 0.16
|
0.23
|
0.79 ± 0.13
|
0.76 ± 0.16
|
0.49
|
- Values presented as Mean ± SD. p-values: paired t test
- Bold values are statistically significant p < 0.05
