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Fig. 2 | Journal of Clinical Movement Disorders

Fig. 2

From: Diagnosing the frontal variant of Alzheimer’s disease: a clinician’s yellow brick road

Fig. 2

fvAD and bvFTD in the Wizard of Oz. a fvAD Scarecrow was searching for a brain because he had none, and without a brain he had no memory or object knowledge. While his phonemic fluency was preserved, fvAD Scarecrow had difficulty with semantics and was irritable and paranoid, believing the crows were gearing to bothering and stealing from him. Furthermore, fvAD Scarecrow was very tremulous (myoclonus). The wind could suddenly jolt him (stimulus-sensitive myoclonus). b bvFTD Tin Man had no heart, so his behavior and emotions were affected from the outset. The “heartless” bvFTD Tin Man lacked empathy and was very ritualistic, only going out to chop wood. His rituals included hyperphagia, making him heavier than the straw-filled fvAD Scarecrow. Furthermore, bvFTD Tin Man was insufficiently lubricated, making him appear parkinsonian. This particular bvFTD Tin Man was missing progranulin, rendering his frontotemporal region asymmetric, as judged by a crooked hat. Both images are from 1900; US Copyright law on public domain

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