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Table 1 Clinical characteristics of participants

From: Agnosia for head tremor in essential tremor: prevalence and clinical correlates

 

All participants

True positivesd

False negativese

p value*

n

126

20

19

 

Age (years)

72.6 ± 12.4

73.5 ± 15.0

81.5 ± 6.9

0.04a

Female gender

64 (50.8)

15 (75.0)

12 (63.2)

0.50b

White ethnicity

117 (92.9)

19 (95.0)

16 (84.2)

0.34b

Current smoker

6 (4.8)

0 (0.0)

1 (5.3)

0.49b

Education (years)

15.8 ± 2.8

15.6 ± 2.9

14.9 ± 2.5

0.44a

Married

69 (54.8)

7 (35.0)

6 (31.6)

0.86b

Lives alone

42 (33.3)

12 (60.0)

9 (47.4)

0.43b

Currently in work force

26 (20.6)

3 (15.0)

1 (5.3)

0.61b

Years since last hospitalization

10.7 ± 14.5 [4.0]

7.6 ± 12.1 [3.0]

12.8 ± 21.8 [4.0]

0.36c

Answered “yes” to the question “Does anyone in your family have tremor?”

83 (65.9)

14 (70.0)

10 (52.6)

0.27b

Age first noticed tremor (years)

39.5 ± 20.1

41.3 ± 21.5

41.4 ± 16.9

0.98a

Duration of tremor (years)

33.2 ± 19.1

32.3 ± 21.9

40.0 ± 17.7

0.25a

Answered “yes” to the question “Does your tremor embarrass you?”

67 (53.2)

11 (55.0)

12 (63.2)

0.61b

Answered “yes” to “Does your voice almost always tremble when you talk?”

26 (20.6)

9 (50.0)

4 (25.0)

0.13b

Reply to “Do you ever have an internal sensation that you are having a head tremor?”

   

0.016b

No

84 (66.7)

5 (25.0)

12 (63.2)

Yes

42 (33.3)

15 (75.0)

7 (36.8)

Reply to “When you feel your head shaking, do you ever see it in the mirror”?

   

0.002b

No

87 (69.0)

3 (15.0)

12 (63.2)

Yes

39 (31.0)

17 (85.0)

7 (36.8)

Reply to “How often do you feel nervous or anxious?”

   

0.36b

Never/No

48 (38.1)

6 (30.0)

8 (42.1)

Rarely

17 (13.5)

4 (20.0)

2 (10.5)

Sometimes

34 (27.0)

6 (30.0)

7 (36.8)

Frequently

16 (12.7)

1 (5.0)

2 (10.5)

Always/Yes

11 (8.7)

3 (15.0)

0 (0.0)

CESD score

9.0 ± 5.7

8.8 ± 5.0

9.0 ± 5.8

0.91a

Severity rating of head tremor (examination)f

   

0.81b

1 (mild)

17 (13.5)

8 (40.0)

9 (47.4)

2 (moderate)

19 (15.1)

10 (50.0)

9 (47.4)

3 (severe)

3 (2.4)

2 (10.0)

1 (5.3)

Total tremor score (examination)

21.1 ± 6.2

23.9 ± 6.5

21.05 ± 6.7

0.19a

Folstein Mini Mental Status Examination Score

28.4 ± 1.9 [29.0]

29.0 ± 1.6 [30.0]

27.6 ± 1.9 [28.0]

0.01c

  1. All values represent means ± standard deviations [median] or numbers (percentage)
  2. Center for Epidemiological Studies Depression Scale
  3. *Comparing true positives vs. false negatives
  4. aStudent’s t test
  5. bChi square test or Fisher’s Exact test
  6. cMann Whitney test
  7. dTrue positives were cases who exhibited head tremor on examination and who were aware of that tremor when questioned
  8. eFalse negatives were patients who exhibited head tremor on examination but were unaware of it
  9. fBased on 39 ET cases with head tremor on examination at Time point 1