Freezing of gait and white matter changes: a tract-based spatial statistics study

Table 4 Multilinear regression analysis

Diffusion measure	Area	Variables	Coefficient	T	P
FA	left SLF	FOGQ	−0.81	−3.7	0.003*
		MMSE	0.43	2.0	0.067
		SL	−0.42	−1.8	0.092
		DST/GC	−0.30	−1.3	0.20
		Cad	−0.18	−0.99	0.34
		SW	0.14	0.76	0.46
FA	right CC	FOGQ	−0.57	−2.7	0.018*
		MMSE	0.60	3.4	0.005*
		SL	−0.27	−1.2	0.23
		DST/GC	0.02	0.093	0.93
		Cad	0.03	0.18	0.86
		SW	−0.18	−1.0	0.32
FA	left CP	FOGQ	−0.90	−4.28	<0.001*
		MMSE	0.45	2.0	0.071
		SL	−0.47	−2.2	0.063
		DST/GC	−0.08	−0.38	0.71
		Cad	−0.18	−1.1	0.30
		SW	−0.01	−0.06	0.95
MD	left PLIC	FOGQ	0.73	3.4	0.005*
		MMSE	−0.37	−2.1	0.07
		SL	0.15	0.64	0.53
		DST/GC	0.11	0.50	0.62
		Cad	0.16	0.92	0.38
		SW	0.03	0.18	0.86
MD	right cingulum	FOGQ	0.91	4.4	<0.001*
		MMSE	−0.26	−1.3	0.21
		SL	0.17	0.81	0.44
		DST/GC	0.11	0.55	0.59
		Cad	0.04	0.26	0.80
		SW	−0.37	−2.1	0.08
AD	left SCR	FOGQ	0.96	3.7	0.003*
		MMSE	0.05	0.22	0.83
		SL	0.21	0.76	0.46
		DST/GC	−0.17	−0.63	0.54
		Cad	−0.06	−0.3	0.77
		SW	0.14	0.65	0.53
RD	left SCR	FOGQ	0.69	2.7	0.019*
		MMSE	−0.08	−0.39	0.71
		SL	−0.06	−0.21	0.84
		DST/GC	0.12	0.48	0.64
		Cad	0.02	0.11	0.91
		SW	−0.07	−0.32	0.75

The table shows the results of multilinear regression analysis of all those six independent variables using average activation of each area in which significant local correlation between FOGQ and FA was found as a dependent variable. The significant P-values are noted by an asterisk.
FOGQ: Freezing of Gait Questionnaire, MMSE: Mini-Mental State Examination, SL: stride length, DST/GC: double support time/gait cycle, cad: cadence, SW: stride width.

ISSN: 2054-7072