Figure 1
From: Writer’s cramp as a presentation of L-2-hydroxyglutaric aciduria
Panels A to E reveal the MRI of patient 1. A and B, axial sections of T2-weighted images (T2WI); C, mid-sagittal plane of T2WI; D and E, coronal sections of T1WI and T2WI, respectively; F, MR spectroscopy of voxel at subcortical white matter. MRI shows white matter changes in subcortical region diffusely, seen as hypointense and hyperintense signal on T1WI and T2WI, respectively. There is sparing of central white matter. There is also T2-hyperintense signal at bilateral dentate nuclei (panel A).