Table 2 Resting state fMRI articles focusing on depression in PD
From: What light have resting state fMRI studies shed on cognition and mood in Parkinson’s disease?
Authors | Year | Analysis method | Participants (Age in years, mean; SD) | Dopamine medication status | PD Duration (Years, mean; SD) | Head motion inclusion criteria; between-group motion comparison |
|---|---|---|---|---|---|---|
Skidmore et al. | 2011 | ALFF | 15 PD (62; 9) | OFF | NR | <1.5% coefficient of variance; NA |
Wen et al. | 2013 | ALFF | 17 PD depressed (64.4; 13.4) | OFF | PD depressed (6.4; 5.4) | <2 mm displacement each in translational or rotational and <2° during whole scan; found no significant differences between groups. |
16 PD non-depressed (60.7; 18.7) | PD non-depressed (5.6; 7.4) | |||||
21 HC (55.4; 16.4) | ||||||
Luo et al. | 2014 | ALFF | 29 PD depressed (51.46; 8.21) | Naïve | PD depressed (1.98; 1.64) | <1.5 mm and <1.5° displacement in any direction; found no significant differences between groups. |
30 PD non-depressed (53.64; 10.18) | PD non-depressed (2.12; 1.30) | |||||
30 HC (51.9; 7.7) | ||||||
Luo et al. | 2014 | Seed FC | 52 PD (52.28; 9.41) | Naïve | PD (1.94; 1.47) | <1.5 mm and <1.5° displacement in any direction; NR. |
52 HC (51.17; 9.23) | ||||||
Sheng et al. | 2014 | ReHo | 20 PD depressed (55.9; 7.4) | OFF | PD depressed (3.4; 1.7) | <2 mm or 2°displacement in any direction; no significant differences between groups. |
21 PD non-depressed (57.3; 6.1) | PD non-depressed (4.0; 2.4) | |||||
25 HC (56.7; 5.3) |