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Table 2 Resting state fMRI articles focusing on depression in PD

From: What light have resting state fMRI studies shed on cognition and mood in Parkinson’s disease?

Authors Year Analysis method Participants (Age in years, mean; SD) Dopamine medication status PD Duration (Years, mean; SD) Head motion inclusion criteria; between-group motion comparison
Skidmore et al. 2011 ALFF 15 PD (62; 9) OFF NR <1.5% coefficient of variance; NA
Wen et al. 2013 ALFF 17 PD depressed (64.4; 13.4) OFF PD depressed (6.4; 5.4) <2 mm displacement each in translational or rotational and <2° during whole scan; found no significant differences between groups.
16 PD non-depressed (60.7; 18.7) PD non-depressed (5.6; 7.4)
21 HC (55.4; 16.4)
Luo et al. 2014 ALFF 29 PD depressed (51.46; 8.21) Naïve PD depressed (1.98; 1.64) <1.5 mm and <1.5° displacement in any direction; found no significant differences between groups.
30 PD non-depressed (53.64; 10.18) PD non-depressed (2.12; 1.30)
30 HC (51.9; 7.7)
Luo et al. 2014 Seed FC 52 PD (52.28; 9.41) Naïve PD (1.94; 1.47) <1.5 mm and <1.5° displacement in any direction; NR.
52 HC (51.17; 9.23)
Sheng et al. 2014 ReHo 20 PD depressed (55.9; 7.4) OFF PD depressed (3.4; 1.7) <2 mm or 2°displacement in any direction; no significant differences between groups.
21 PD non-depressed (57.3; 6.1) PD non-depressed (4.0; 2.4)
25 HC (56.7; 5.3)
  1. NR: not reported, NA: not applicable.