Table 1 Resting state fMRI articles focusing on cognitive impairment in PD
From: What light have resting state fMRI studies shed on cognition and mood in Parkinson’s disease?
Authors | Year | Analysis method | Participants (Age in years, mean; SD) | Dopamine medication status | PD Duration (Years, mean; SD) | Controlled for depression | Head motion inclusion criteria; between-group motion comparison |
|---|---|---|---|---|---|---|---|
Krajcovicova et al. | 2011 | ICA | 18 PD (63.50; 9.07) | ON | PD (5.4; 0.31) | Yes | NR; NR |
18 control (60.89; 6.67) | |||||||
Seibert et al. | 2011 | ICA, | 19 PD (72; 7) | NR | NR | No | NR; NR |
VBM | 18 PRD (70; 8) | ||||||
19 control (76; 9) | |||||||
Rektorova et al. | 2012 | Seed FC | 18 PD (63.5; 9.07) | ON | PD (4.44; NR) | No | NR; NR |
14 PDD (72.36; 5.88) | PDD (9.64; NR) | ||||||
18 control (60.89; 6.67) | |||||||
Tessitore et al. | 2012 | ICA, VBM | 16 PD (64.15; 1.64) | ON | PD (5.4; 0.31) | Yes | NR; NR |
16 control (65.5; 6.17) | |||||||
Baggio et al. | 2014 | Graph theory | 43 PD no-CI (64; 9.8) | ON | PD no-CI (6.1; 4.4) | Yes* | Root mean square <0.3 mm translation or .6° rotation; significant difference found between PD no-CI and controls. |
23 PD CI (66.7; 12.2) | PD CI (9.0; 5.5) | ||||||
36 control (63.4; 10.5) | |||||||
Lebedev et al. | 2014 | Graph theory | 30 PD (61.67; 9.46) | Naïve | Newly diagnosed, not otherwise specified | No | NR; NA |
Yao et al. | 2014 | ICA | 12 PD non-visual hallucinations (63.4; 7.4) | ON | PD non-visual hallucinations (8.4; 5.1) | Yes | < 2.5 mm displacement and <2.5° rotation in any direction. |
12 PD visual hallucinations (67.6; 7.4) | PD visual hallucinations (10.0; 3.5) | Did not mention between-group motion comparisons. | |||||
14 control (64.1; 4.0) |