Table 3 Change in TWSTRS scores and health utility score from baseline to visit 2 and visit 3
Unadjusted Model | Adjusted Modela | |||||
|---|---|---|---|---|---|---|
AboBoNT-A LS Mean (95% CI) | OnaBoNT-A LS Mean (95% CI) | Differenceb (95% CI) | AboBoNT-A LS Mean (95% CI) | OnaBoNT-A LS Mean (95% CI) | Differenceb (95% CI) | |
Change from baseline to visit 2 | ||||||
TWSTRS Scores | ||||||
Total | −15.80 (− 17.04, − 14.57) | −11.00 (− 12.94, − 9.07) | −4.80 (− 7.10, − 2.50) | −15.33 (− 16.53, − 14.13) | −12.17 (− 14.09, − 10.24) | −3.16 (− 5.49, − 0.84) |
Severity Subscale | −8.49 (− 9.08, − 7.90) | −6.75 (− 7.67, − 5.82) | −1.74 (− 2.84, − 0.64) | −8.30 (− 8.88, − 7.71) | −7.21 (− 8.15, − 6.27) | −1.08 (− 2.22, 0.05) |
Disability Subscale | −4.56 (− 5.12, − 3.99) | −2.77 (− 3.65, − 1.88) | −1.79 (− 2.84, − 0.74) | −4.30 (− 4.81, − 3.79) | −3.39 (− 4.21, − 2.57) | − 0.91 (− 1.90, 0.08) |
Pain Subscale | −2.76 (− 3.20, − 2.32) | −1.49 (− 2.18, − 0.80) | −1.27 (− 2.09, − 0.45) | − 2.67 (− 3.04, − 2.30) | − 1.71 (− 2.30, − 1.12) | −0.96 (− 1.68, − 0.25) |
Health Utility Score | 0.050 (0.046, 0.053) | 0.035 (0.028, 0.041) | 0.015 (0.008, 0.022) | 0.048 (0.044, 0.052) | 0.038 (0.032, 0.044) | 0.010 (0.003, 0.017) |
Change from baseline to visit 3 | ||||||
TWSTRS Scores | ||||||
Total | −6.75 (− 7.87, −5.64) | − 3.13 (− 4.87, − 1.40) | −3.62 (− 5.68, − 1.56) | −6.42 (− 7.52, − 5.33) | − 3.94 (− 5.68, − 2.20) | −2.48 (− 4.57, − 0.39) |
Severity Subscale | −3.70 (− 4.21, − 3.19) | −2.02 (− 2.81, − 1.22) | −1.68 (− 2.63, − 0.74) | −3.55 (− 4.06, − 3.05) | −2.38 (− 3.18, − 1.58) | −1.18 (− 2.14, − 0.22) |
Disability Subscale | − 1.93 (− 2.43, − 1.42) | −0.63 (− 1.42, 0.16) | −1.30 (− 2.23, − 0.36) | −1.78 (− 2.27, − 1.29) | −1.00 (− 1.78, − 0.22) | −0.78 (− 1.71, 0.16) |
Pain Subscale | −1.12 (− 1.59, − 0.66) | −0.48 (− 1.20, 0.24) | −0.64 (− 1.50, 0.21) | −1.04 (− 1.45, − 0.62) | −0.70 (− 1.36, − 0.04) | −0.34 (− 1.13, 0.45) |
Health Utility Score | 0.021 (0.018, 0.025) | 0.010 (0.004, 0.015) | 0.011 (0.005, 0.018) | 0.020 (0.017, 0.024) | 0.012 (0.007, 0.018) | 0.008 (0.001, 0.014) |